Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.55 |
| ▸ | RARG | P13631 | 5/20 | 0.55 |
| ▸ | RXRA | P19793 | 7/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049069 | 0.80 | RARA (0.67) | RARARARBRARGRXRARXRB | |
| SCHEMBL17049065 | 0.76 | RXRA (0.58) | RARARARBRARGRXRARXRB | |
| SCHEMBL17049079 | 0.76 | RXRA (0.67) | RARARARBRARGRXRARXRB | |
| SCHEMBL10846840 | 0.71 | RARA (0.72) | RARARARBRARGRXRARXRB | |
| SCHEMBL10846838 | 0.71 | RARA (0.72) | RARARARBRARGRXRARXRB | |
| SCHEMBL156460 | 0.71 | RARB (1.00) | RARARARBRARGRXRARXRB | |
| SCHEMBL10841477 | 0.71 | RARB (1.00) | RARARARBRARGRXRARXRB | |
| SCHEMBL4666958 | 0.71 | RARB (0.75) | RARARARBRARGRXRARXRB | |
| SCHEMBL2594345 | 0.71 | RARB (0.75) | RARARARBRARGRXRARXRB | |
| Hydrochloric Acid SCHEMBL4432609 | 0.70 | RARB (0.97) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015130973-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-09-03 | — | — | WO | disclosed |