Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 1.00 |
| ▸ | RXRB | P28702 | 15/20 | 1.00 |
| ▸ | RXRG | P48443 | 15/20 | 1.00 |
| ▸ | RARB | P10826 | 5/20 | 0.55 |
| ▸ | RARG | P13631 | 5/20 | 0.55 |
| ▸ | RARA | P10276 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049092 | 0.88 | RXRA (0.79) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL20411348 | 0.88 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17053967 | 0.87 | RXRA (0.77) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17049097 | 0.85 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17049098 | 0.84 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17053989 | 0.83 | RXRA (1.00) | RXRARXRBRXRGPPARG | |
| SCHEMBL17049085 | 0.82 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5179730 | 0.79 | RXRA (0.83) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17049064 | 0.77 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL17049060 | 0.76 | RXRA (0.78) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097219-A1 | COMPOSITIONS AND METHODS FOR TREATING NF1 AND OTHER CONDITIONS | LIBY KAREN (US) | 2024-05-10 | — | — | WO | disclosed |
| US-10238655-B2 | Dihydroindene and tetrahydronaphthalene compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180207156-A1 | DIHYDROINDENE AND TETRAHYDRONAPHTHALENE COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-07-26 | — | — | US | disclosed |
| US-20180207156-A1 | DIHYDROINDENE AND TETRAHYDRONAPHTHALENE COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-07-26 | — | — | US | disclosed |
| US-10005741-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-06-26 | — | — | US | disclosed |
| US-10005741-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-06-26 | — | — | US | disclosed |
| US-10005741-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-06-26 | — | — | US | disclosed |
| US-20180141921-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180141921-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180141921-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-24 | — | — | US | disclosed |
| US-9908856-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-06 | — | — | US | disclosed |
| US-9908856-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-06 | — | — | US | disclosed |
| US-9908856-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170008859-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-01-12 | — | — | US | disclosed |
| US-20170008859-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-01-12 | — | — | US | disclosed |
| US-20170008859-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-01-12 | — | — | US | disclosed |
| WO-2015130973-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-09-03 | — | — | WO | disclosed |
| WO-2015130973-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008859-A1 | THERAPEUTIC COMPOUNDS | IAPP, PARK7, NLN | RXRA 674/4885RXRB 644/4885RXRG 545/4885 |
| US-20180207156-A1 | DIHYDROINDENE AND TETRAHYDRONAPHTHALENE COMPOUNDS | DHPS, DHODH, APP | RXRA 3174/4885RXRB 3240/4885RXRG 3620/4885 |
| US-20180141921-A1 | THERAPEUTIC COMPOUNDS | IAPP, PARK7, NLN | RXRA 674/4885RXRB 644/4885RXRG 545/4885 |
| US-10005741-B2 | Therapeutic compounds | IAPP, PARK7, NLN | RXRA 674/4885RXRB 644/4885RXRG 545/4885 |
| US-10238655-B2 | Dihydroindene and tetrahydronaphthalene compounds | DHPS, DHODH, APP | RXRA 3174/4885RXRB 3240/4885RXRG 3620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.