SCHEMBL17049294

SCHEMBL17049294

O=CN(c1ccccc1)c1cc[nH]n1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28844432 0.80 TSHR (0.32)
SCHEMBL27922845 0.75
SCHEMBL5516786 0.75 ALDH1A1 (0.42) POLB
SCHEMBL43388 0.75 ALDH1A1 (0.42) POLB
SCHEMBL10418486 0.74 POLB (0.40) POLB
SCHEMBL22576681 0.74
SCHEMBL9183270 0.73 ALDH1A1 (0.44) POLB
SCHEMBL4690140 0.71 NPSR1 (0.32) POLB
SCHEMBL17674048 0.71 DHFR (0.42)
SCHEMBL29006138 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970650-A Pyrazole phenyl formamide analog derivative and its preparation method and application 南开大学 2019-07-05 CN claimed
CN-104628646-A N-pyrazolyl formanilide compound, intermediate, composition, preparation method and application SHANGHAI INSITITUTE OF ORGANIC CHEMISTRY CHINESE ACADEMY OF SCIENCES 2015-05-20 CN claimed
CN-1255384-C N-pyrazolylcarboxanilides as fungicides BAYER AGRICULTURE CORP SCIENCE (DE) 2006-05-10 CN claimed
CN-1533380-A N-pyrazolylcarboxanilides as fungicides �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-09-29 CN claimed
CN-119330836-A Preparation method of 2-substituted alkane aniline compound 帕潘纳(北京)科技有限公司 2025-01-21 CN disclosed
CN-109970650-A Pyrazole phenyl formamide analog derivative and its preparation method and application 南开大学 2019-07-05 CN disclosed
CN-109970650-A Pyrazole phenyl formamide analog derivative and its preparation method and application 南开大学 2019-07-05 CN disclosed
CN-109970650-A Pyrazole phenyl formamide analog derivative and its preparation method and application 南开大学 2019-07-05 CN disclosed
EP-3110816-A1 N2-PHENYL-PYRIDO[3,4-D]PYRIMIDINE-2,8-DIAMINE DERIVATIVES AND THEIR USE AS MPS1 INHIBITORS Cancer Research Technology Ltd (GB) 2017-01-04 EP disclosed
WO-2015128676-A1 N2-PHENYL-PYRIDO[3,4-D]PYRIMIDINE-2,8-DIAMINE DERIVATIVES AND THEIR USE AS MPS1 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2015-09-03 WO disclosed
CN-104628646-A N-pyrazolyl formanilide compound, intermediate, composition, preparation method and application SHANGHAI INSITITUTE OF ORGANIC CHEMISTRY CHINESE ACADEMY OF SCIENCES 2015-05-20 CN disclosed
CN-1255384-C N-pyrazolylcarboxanilides as fungicides BAYER AGRICULTURE CORP SCIENCE (DE) 2006-05-10 CN disclosed
CN-1255384-C N-pyrazolylcarboxanilides as fungicides BAYER AGRICULTURE CORP SCIENCE (DE) 2006-05-10 CN disclosed
CN-1533380-A N-pyrazolylcarboxanilides as fungicides �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-09-29 CN disclosed
CN-1533380-A N-pyrazolylcarboxanilides as fungicides �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-09-29 CN disclosed