Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049376 | 0.79 | — | — | |
| SCHEMBL10448589 | 0.74 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28680876 | 0.74 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11324700 | 0.73 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL29234277 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL29069306 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11327083 | 0.73 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL12568607 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11938274 | 0.71 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10775397 | 0.70 | CHRM2 (0.35) | TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060477-B2 | Epoxide hydrolases of aspergillus origin | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-06-13 | — | — | US | disclosed |
| US-20030143710-A1 | Epoxide hydrolases of aspergillus origin | UNIVERSITE DE LA MEDITERRANEE (FR) | 2003-07-31 | — | — | US | disclosed |
| US-4904679-A | Pyrrolophenylalkanolamines as animal yield promoters | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| EP-0289850-A2 | Pyrrololphenylalkanol amines and their derivatives, process for their preparation and their use as performance promotors | BAYER AG (DE) | 1988-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030143710-A1 | Epoxide hydrolases of aspergillus origin | EPHX1, EPHX2, ERG28 | SMN1; SMN2 4878/4885ALDH1A1 475/4885THRB 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.