Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23394808 | 0.93 | GABRR1 (0.50) | GABRR1ACECYP2C19POLBGABRR2 | |
| SCHEMBL1817654 | 0.93 | GABRR1 (0.50) | GABRR1ACECYP2C19POLBGABRR2 | |
| SCHEMBL1963027 | 0.84 | GABRR1 (0.58) | GABRR1ACECYP2C19GABRR2CYP1A2 | |
| SCHEMBL6864216 | 0.84 | GABRR1 (0.50) | GABRR1CYP2C19POLBGABRR2TDP1 | |
| Hydrochloric Acid SCHEMBL2384923 | 0.82 | GABRR1 (0.48) | GABRR1CYP2C19POLBGABRR2TDP1 | |
| Hydrochloric Acid SCHEMBL2885177 | 0.82 | GABRR1 (0.48) | GABRR1CYP2C19POLBGABRR2TDP1 | |
| Hydrochloric Acid SCHEMBL3795818 | 0.82 | GABRR1 (0.55) | GABRR1ACECYP2C19GABRR2CYP1A2 | |
| SCHEMBL22039 | 0.79 | GABRR1 (0.50) | GABRR1CYP2C19POLBGABRR2TDP1 | |
| SCHEMBL2697233 | 0.79 | GABRR1 (0.50) | GABRR1CYP2C19POLBGABRR2TDP1 | |
| SCHEMBL8628131 | 0.79 | GABRR1 (0.50) | GABRR1CYP2C19POLBGABRR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9119391-B1 | Polymer coated ceria nanoparticles for selective cytoprotection | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-09-01 | — | — | US | disclosed |