Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2384923 | 1.00 | GABRR1 (0.48) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL6864216 | 0.97 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| Hydrochloric Acid SCHEMBL3793595 | 0.94 | GABRR1 (0.48) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL9782991 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL2697233 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL503468 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL22039 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL8628131 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL13084744 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA | |
| SCHEMBL770971 | 0.90 | GABRR1 (0.50) | GABRR1POLBTDP1GABRR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352957-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES, INC. (JP) | 2025-11-20 | — | — | US | disclosed |
| EP-4534187-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR PRODUCING SAME | Toray Industries, Inc. (JP) | 2025-04-09 | — | — | EP | disclosed |
| US-12186711-B2 | Composite semipermeable membrane | TORAY INDUSTRIES, INC. (JP) | 2025-01-07 | — | — | US | disclosed |
| US-12161978-B2 | Composite semipermeable membrane | TORAY INDUSTRIES, INC. (JP) | 2024-12-10 | — | — | US | disclosed |
| US-12138595-B2 | Composite semipermeable membrane | TORAY INDUSTRIES, INC. (JP) | 2024-11-12 | — | — | US | disclosed |
| WO-2024204209-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, METHOD FOR PRODUCING COMPOSITE SEMIPERMEABLE MEMBRANE, COMPOSITE SEMIPERMEABLE MEMBRANE ELEMENT, AND COMPOSITE SEMIPERMEABLE MEMBRANE MODULE | 東レ株式会社 | 2024-10-03 | — | — | WO | disclosed |
| US-20240325977-A1 | CONCENTRATION METHOD FOR ANALYSIS SOLUTION USING FORWARD OSMOSIS MEMBRANE, AND ANALYSIS METHOD | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-10-03 | — | — | US | disclosed |
| US-20240278184-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE | TORAY INDUSTRIES, INC. (JP) | 2024-08-22 | — | — | US | disclosed |
| US-20240269619-A1 | Forward Osmosis Membrane and Forward Osmosis Membrane Module Including Same | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-08-15 | — | — | US | disclosed |
| US-20240269618-A1 | Forward Osmosis Membrane and Forward Osmosis Membrane Module Including Same | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-08-15 | — | — | US | disclosed |
| US-20070284309-A1 | Composite Semipermeable Membrane, Production Process Thereof, And Element, Fluid Separation Equipment And Method For Water Treatment Using The Same | TORAY INDUSTRIES, INC. (JP) | 2007-12-13 | — | — | US | disclosed |
| US-7279097-B2 | Composite semipermeable membrane, and production process thereof | TORAY INDUSTRIES, INC. (JP) | 2007-10-09 | — | — | US | disclosed |
| EP-1819428-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND METHOD FOR WATER TREATMENT USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1812149-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051888-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-18 | — | — | WO | disclosed |
| WO-2006046781-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND METHOD FOR WATER TREATMENT USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-04 | — | — | WO | disclosed |
| US-20040256309-A1 | Composite semipermeable membrane, and production process thereof | TORAY INDUSTRIES, INC. (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1488846-A1 | Composite semipermeable membrane, and production process thereof | TORAY INDUSTRIES, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6521130-B1 | Desalination of seawater and brackish water, the production of ultra-pure water for use in semiconductor washing and the like, | TORAY INDUSTRIES, INC. (JP) | 2003-02-18 | — | — | US | disclosed |
| EP-1157734-A1 | PROCESS FOR PRODUCING COMPOSITE SEMIPERMEABLE MEMBRANE | TORAY INDUSTRIES, INC. (JP) | 2001-11-28 | — | — | EP | disclosed |