SCHEMBL1817654

SCHEMBL1817654

O=C(O)C1CC(C(=O)O)C(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.50
CYP2C19 P33261 3/20 0.38
POLB P06746 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
GABRR2 P28476 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALOX15 P16050 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
ACE P12821 1/20 0.35
TSHR P16473 2/20 0.35
PMP22 Q01453 2/20 0.35
APLNR P35414 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23394808 1.00 GABRR1 (0.50) GABRR1CYP2C19POLBTDP1GABRR2
SCHEMBL17049779 0.93 GABRR1 (0.44) GABRR1CYP2C19POLBTDP1GABRR2
SCHEMBL1963027 0.85 GABRR1 (0.58) GABRR1CYP2C19GABRR2CYP1A2CYP2D6
SCHEMBL6864216 0.85 GABRR1 (0.50) GABRR1CYP2C19POLBTDP1GABRR2
SCHEMBL3237860 0.84 GABRR1 (0.41) GABRR1CYP2C19POLBTDP1GABRR2
Hydrochloric Acid SCHEMBL2384923 0.82 GABRR1 (0.48) GABRR1CYP2C19POLBTDP1GABRR2
Hydrochloric Acid SCHEMBL3795818 0.82 GABRR1 (0.55) GABRR1CYP2C19GABRR2CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL2885177 0.82 GABRR1 (0.48) GABRR1CYP2C19POLBTDP1GABRR2
SCHEMBL2697233 0.79 GABRR1 (0.50) GABRR1CYP2C19POLBTDP1GABRR2
SCHEMBL9782991 0.79 GABRR1 (0.50) GABRR1CYP2C19POLBTDP1GABRR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114044913-A Metal-organic framework material and preparation method thereof 广东美的白色家电技术创新中心有限公司 2022-02-15 CN claimed
US-7939242-B2 barrier film material includes, in addition to an alkali-soluble polymer, a multivalent carboxylic acid compound having a plurality of carboxyl groups or a multivalent alcohol compound. The multivalent carboxylic acid compound or the multivalent alcohol compound is adhered onto the surface of a resist PANASONIC CORPORATION (JP) 2011-05-10 US claimed
US-20080233491-A1 BARRIER FILM MATERIAL AND PATTERN FORMATION METHOD USING THE SAME RPX CORPORATION 2008-09-25 US claimed
US-6927012-B2 Polyamic acid resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-09 US claimed
US-6875554-B2 Positive photosensitive polyimide resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-04-05 US claimed
EP-3699232-B1 RESIN COMPOSITION AND MOLDED ARTICLE MITSUBISHI CHEM CORP (JP) 2024-04-03 EP disclosed
CN-111108151-B Resin composition and molded article 三菱工程塑料株式会社 2023-06-09 CN disclosed
CN-111108152-B Resin composition and molded article 三菱工程塑料株式会社 2023-03-31 CN disclosed
CN-110554537-B Varnish for photo-alignment film and liquid crystal display device 株式会社日本显示器 2022-05-10 CN disclosed
CN-111690321-B Varnish for photo-alignment film and liquid crystal display device 株式会社日本显示器 2022-02-08 CN disclosed
CN-111690321-A Varnish for photo-alignment film and liquid crystal display device 株式会社日本显示器 2020-09-22 CN disclosed
EP-3699233-A1 RESIN COMPOSITION AND MOLDED ARTICLE Mitsubishi Engineering-Plastics Corporation (JP) 2020-08-26 EP disclosed
EP-0313474-A2 An optical article exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-04-26 EP disclosed
EP-0313475-A2 An optical article containing a transmission medium exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-04-26 EP disclosed
EP-0313476-A2 An optical article containing a polymeric matrix exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-04-26 EP disclosed
US-4796971-A CHARGE TRANSFER COMPOUND ON CROSSLINKED MATRIX EASTMAN KODAK COMPANY (US) 1989-01-10 US disclosed
US-4792208-A POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR EASTMAN KODAK COMPANY (US) 1988-12-20 US disclosed
EP-0129234-B1 ELECTROPHOTOGRAPHIC ELEMENTS HAVING BARRIER LAYERS OF CROSSLINKED POLYMERS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-11-04 EP disclosed
EP-0129234-A1 Electrophotographic elements having barrier layers of crosslinked polymers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-12-27 EP disclosed
US-4485161-A Electrophotographic elements having barrier layers of crosslinked polymers of aliphatic or aromatic monomers containing α,β-ethylenically unsaturated carbonyl-containing substituents EASTMAN KODAK COMPANY (US) 1984-11-27 US disclosed