Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.61 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.61 |
| ▸ | UNG | P13051 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049785 | 0.94 | UNG (0.55) | TRIM24TRIM33UNGALDH1A1DHODH | |
| SCHEMBL17167118 | 0.92 | UNG (0.53) | TRIM24TRIM33UNGALDH1A1DHODH | |
| SCHEMBL1495719 | 0.91 | DHODH (0.54) | TRIM24TRIM33UNGALDH1A1DHODH | |
| SCHEMBL31532963 | 0.88 | TRIM24 (0.71) | TRIM24TRIM33UNGALDH1A1ERN1 | |
| SCHEMBL16434649 | 0.83 | UNG (0.61) | TRIM24TRIM33UNGALDH1A1ERN1 | |
| SCHEMBL3470017 | 0.83 | UNG (0.61) | TRIM24TRIM33UNGALDH1A1ERN1 | |
| SCHEMBL2558001 | 0.82 | AURKA (0.55) | TRIM24TRIM33UNGALDH1A1DHODH | |
| SCHEMBL19188845 | 0.81 | TRIM24 (0.47) | TRIM24TRIM33UNGALDH1A1DHODH | |
| SCHEMBL2556774 | 0.80 | RXRA (0.61) | TRIM24TRIM33UNGALDH1A1DHODH | |
| SCHEMBL15333055 | 0.80 | ALDH1A1 (0.53) | TRIM24TRIM33UNGALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120080-B2 | Acetylene storage using metal-organic frameworks with open metal sites | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-09-01 | — | — | US | disclosed |