Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807849 | 0.86 | PDK2 (0.41) | HTTPDK2RIPK2EGFRTGFBR1 | |
| SCHEMBL807854 | 0.84 | PDK2 (0.39) | ALDH1A1GAAHTTPDK2ESR2 | |
| SCHEMBL21368218 | 0.84 | PDK2 (0.43) | HTTPDK2MAPK14NPSR1 | |
| SCHEMBL25657060 | 0.83 | PDK2 (0.49) | ALDH1A1GAAALOX15HTTTDP1 | |
| SCHEMBL9883238 | 0.83 | MAPK14 (0.45) | ALDH1A1GAAALOX15HTTTDP1 | |
| SCHEMBL29518397 | 0.83 | PDK2 (0.54) | ALDH1A1ALOX15HTTTDP1PDK2 | |
| SCHEMBL808129 | 0.83 | PDK2 (0.54) | ALDH1A1ALOX15HTTTDP1PDK2 | |
| SCHEMBL15840195 | 0.81 | FABP3 (0.41) | ALDH1A1GAAALOX15HTTTDP1 | |
| SCHEMBL796163 | 0.80 | PDK2 (0.44) | PDK2MAPK14MAPK8MAPK10 | |
| SCHEMBL29518615 | 0.80 | PDK2 (0.51) | ALDH1A1ALOX15TDP1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10957864-B2 | Materials for organic light-emitting devices | MERCK PATENT GMBH (DE) | 2021-03-23 | — | — | US | disclosed |
| US-20190326521-A1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2019-10-24 | — | — | US | disclosed |
| EP-3110796-B1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |
| US-20170012219-A1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2017-01-12 | — | — | US | disclosed |
| US-20170012219-A1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2017-01-12 | — | — | US | disclosed |
| WO-2015128052-A1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10957864-B2 | Materials for organic light-emitting devices | L1CAM, EML4, OR10J3 | ALDH1A1 155/4885GAA 2400/4885ALOX15 1257/4885 |
| US-20190326521-A1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | L1CAM, EML4, OR10J3 | ALDH1A1 155/4885GAA 2400/4885ALOX15 1257/4885 |
| US-20170012219-A1 | MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | L1CAM, EML4, OR10J3 | ALDH1A1 155/4885GAA 2400/4885ALOX15 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.