Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15183718 | 0.96 | PDK2 (0.44) | PDK2FABP3FABP4FABP5MAPK13 | |
| SCHEMBL29767840 | 0.94 | PDK2 (0.44) | PDK2FABP3FABP4FABP5SIRT2 | |
| SCHEMBL796163 | 0.94 | PDK2 (0.44) | PDK2FABP3FABP4FABP5SIRT2 | |
| SCHEMBL807849 | 0.92 | PDK2 (0.41) | PDK2SIRT2SIRT1MEN1APAF1 | |
| SCHEMBL18212129 | 0.90 | PDK2 (0.40) | PDK2FABP3FABP4FABP5SIRT2 | |
| SCHEMBL16926140 | 0.87 | PDK2 (0.42) | PDK2FABP3FABP4FABP5MAPK13 | |
| SCHEMBL30353956 | 0.87 | PDK2 (0.42) | PDK2FABP3FABP4FABP5MAPK13 | |
| SCHEMBL18212136 | 0.86 | PDK2 (0.39) | PDK2SIRT2SIRT1MEN1APAF1 | |
| SCHEMBL17733307 | 0.86 | PDK2 (0.40) | PDK2FABP3FABP4FABP5SIRT2 | |
| SCHEMBL22662302 | 0.86 | PDK2 (0.41) | PDK2FABP3FABP4FABP5MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11302870-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2022-04-12 | — | — | US | disclosed |
| US-20200048207-A1 | COMPOUNDS WITH ARYLAMINE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20190288206-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11302870-B2 | Materials for electronic devices | EFNA1, PNMT, FLNB | PDK2 866/4885FABP3 2911/4885FABP4 3539/4885 |
| US-20200048207-A1 | COMPOUNDS WITH ARYLAMINE STRUCTURES | DDT, NAT1, INMT | PDK2 951/4885FABP3 4740/4885FABP4 4460/4885 |
| US-20190288206-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, PNMT, FLNB | PDK2 833/4885FABP3 2971/4885FABP4 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.