Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ACACB | O00763 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17050837 | 0.88 | ACACB (0.62) | KDM4EALDH1A1L3MBTL1ACACBCYP2C9 | |
| SCHEMBL17050839 | 0.81 | TTR (0.48) | KDM4EALDH1A1L3MBTL1ACACBCYP2C9 | |
| SCHEMBL8016820 | 0.80 | KDM4E (0.77) | KDM4EALDH1A1L3MBTL1CYP2C9MAPT | |
| SCHEMBL17050452 | 0.80 | MAPK8 (0.43) | KDM4EALDH1A1L3MBTL1ACACBCYP2C9 | |
| SCHEMBL8006810 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1L3MBTL1ACACBMAPT | |
| SCHEMBL21328359 | 0.79 | MAPT (0.68) | KDM4EALDH1A1L3MBTL1CYP2C9MAPT | |
| SCHEMBL16838779 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1L3MBTL1ACACBMAPT | |
| SCHEMBL3692188 | 0.78 | AR (0.45) | KDM4EALDH1A1L3MBTL1ACACBCYP2C9 | |
| SCHEMBL16838772 | 0.78 | ALDH1A1 (0.65) | KDM4EALDH1A1L3MBTL1MAPTFDPS | |
| SCHEMBL21902104 | 0.77 | KMT2A (0.56) | KDM4EALDH1A1L3MBTL1CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | ACSS2, ACACB, ACAT2 | KDM4E 2675/4885ALDH1A1 408/4885L3MBTL1 3849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.