Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976119 | 1.00 | TLR4 (0.39) | TLR4LY96CYP2C19HIF1ASMPD1 | |
| SCHEMBL27282033 | 0.85 | SMPD1 (0.37) | SMPD1 | |
| SCHEMBL17052653 | 0.83 | — | — | |
| SCHEMBL17058711 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL24709744 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL24709746 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL13864486 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL23378918 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL1104569 | 0.81 | SMPD1 (0.45) | SMPD1 | |
| SCHEMBL897909 | 0.80 | TLR4 (0.44) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030444-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS HAVING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS | TRANSLATE BIO MA, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9790494-B2 | Multimeric oligonucleotide compounds having non-nucleotide based cleavable linkers | TRANSLATE BIO MA, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20150315585-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS HAVING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS | RANA THERAPEUTICS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315586-A1 | METHODS OF DELIVERING MULTIPLE TARGETING OLIGONUCLEOTIDES TO A CELL USING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS | RANA THERAPEUTICS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150247141-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS | RANA THERAPEUTICS, INC. (US) | 2015-09-03 | — | — | US | disclosed |