⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976119 | 0.83 | TLR4 (0.39) | — | |
| SCHEMBL17052655 | 0.83 | TLR4 (0.39) | — | |
| SCHEMBL13864486 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL17058711 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL23378918 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL24709744 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL24709746 | 0.82 | LGALS8 (0.33) | — | |
| SCHEMBL17052660 | 0.80 | — | — | |
| SCHEMBL23188294 | 0.77 | LGALS8 (0.31) | — | |
| SCHEMBL23665563 | 0.72 | INPP5A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030444-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS HAVING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS | TRANSLATE BIO MA, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9790494-B2 | Multimeric oligonucleotide compounds having non-nucleotide based cleavable linkers | TRANSLATE BIO MA, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-9186190-B2 | Functionalized nanodiamond reinforced biopolymers | DREXEL UNIVERSITY (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150315586-A1 | METHODS OF DELIVERING MULTIPLE TARGETING OLIGONUCLEOTIDES TO A CELL USING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS | RANA THERAPEUTICS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315585-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS HAVING NON-NUCLEOTIDE BASED CLEAVABLE LINKERS | RANA THERAPEUTICS, INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150247141-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS | RANA THERAPEUTICS, INC. (US) | 2015-09-03 | — | — | US | disclosed |