Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.39 |
| ▸ | ITPR3 | Q14573 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829446 | 1.00 | TLR4 (0.44) | TLR4LY96LGALS8ITPR3 | |
| SCHEMBL898729 | 1.00 | TLR4 (0.44) | TLR4LY96LGALS8ITPR3 | |
| SCHEMBL15631727 | 0.88 | TLR4 (0.39) | TLR4LY96LGALS8 | |
| SCHEMBL15631754 | 0.88 | TLR4 (0.39) | TLR4LY96LGALS8 | |
| SCHEMBL15631732 | 0.88 | TLR4 (0.39) | TLR4LY96LGALS8 | |
| SCHEMBL898764 | 0.87 | FBP1 (0.46) | ITPR3 | |
| SCHEMBL898646 | 0.87 | FBP1 (0.46) | ITPR3 | |
| SCHEMBL118472 | 0.84 | LGALS8 (0.47) | LGALS8ITPR3 | |
| SCHEMBL17052655 | 0.80 | TLR4 (0.39) | TLR4LY96 | |
| SCHEMBL25976119 | 0.80 | TLR4 (0.39) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155334-A1 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | UNIVERSITÉ DE STRASBOURG (FR) | 2014-06-05 | — | — | US | claimed |
| US-20140088036-A1 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | UNIVERSITE DE STRASBOURG (FR) | 2014-03-27 | — | — | US | claimed |
| EP-2621273-A2 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | Normoxys, Inc. (US) | 2013-08-07 | — | — | EP | claimed |
| WO-2012045009-A2 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | NORMOXYS, INC. (US) | 2012-04-05 | — | — | WO | claimed |
| US-20100261682-A1 | Method and Means for the Treatment of Cachexia | BIONERIS AB | 2010-10-14 | — | — | US | claimed |
| US-20210361680-A1 | INOSITOL-BASED IMMUNOTHERAPIES | NORMOXYS INC (US) | 2021-11-25 | — | — | US | disclosed |
| US-20160074421-A1 | METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT | SIRÈN MATTI (FI) | 2016-03-17 | — | — | US | disclosed |
| US-20160067267-A1 | MYO-INOSITOL TRISPYROPHOSPHATE AS AN ANTI-OBESITY AGENT | NORMOXYS, INC. (US) | 2016-03-10 | — | — | US | disclosed |
| US-20140155334-A1 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | UNIVERSITÉ DE STRASBOURG (FR) | 2014-06-05 | — | — | US | disclosed |
| US-20140088036-A1 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | UNIVERSITE DE STRASBOURG (FR) | 2014-03-27 | — | — | US | disclosed |
| EP-2621273-A2 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | Normoxys, Inc. (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012045009-A2 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | NORMOXYS, INC. (US) | 2012-04-05 | — | — | WO | disclosed |
| US-20100261682-A1 | Method and Means for the Treatment of Cachexia | BIONERIS AB | 2010-10-14 | — | — | US | disclosed |
| EP-2187892-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | Bioneris AB (SE) | 2010-05-26 | — | — | EP | disclosed |
| US-20090175924-A1 | COATED STENT | BIONERIS AB (SE) | 2009-07-09 | — | — | US | disclosed |
| WO-2009038533-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | BIONERIS AB (SE) | 2009-03-26 | — | — | WO | disclosed |
| EP-1390045-B1 | THE USE OF A COMPOUND WITH A NEGATIVELY CHARGED DOMAIN OF PHOSPHOROUS-CONTAINING RADICALS FOR THE TREATMENT OF RESTENOSIS | BIONERIS AB (SE) | 2008-12-03 | — | — | EP | disclosed |
| US-20050261756-A1 | Coated stent | BIONERIS AB (SE) | 2005-11-24 | — | — | US | disclosed |
| US-20040235799-A1 | Use of a compound with a negatively charged domain of radicals for the treatment of restenosis | BIONERIS AB (SE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261682-A1 | Method and Means for the Treatment of Cachexia | PYGM, GYS1, CPT1B | TLR4 2430/4885LY96 3278/4885LGALS8 3738/4885 |
| US-20140155334-A1 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | PPIP5K2, INPP5A, INPP5B | TLR4 925/4885LY96 4436/4885LGALS8 2498/4885 |
| US-20160074421-A1 | METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT | TTPA, LPO, HADHB | TLR4 741/4885LY96 865/4885LGALS8 3328/4885 |
| US-20040235799-A1 | Use of a compound with a negatively charged domain of radicals for the treatment of restenosis | PCNA, OPRK1, OGFR | TLR4 358/4885LY96 3381/4885LGALS8 3620/4885 |
| US-20090175924-A1 | COATED STENT | PHOSPHO1, SOST, PLCB3 | TLR4 199/4885LY96 2565/4885LGALS8 3006/4885 |
| US-20140088036-A1 | POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES | PPIP5K2, INPP5A, INPP5B | TLR4 925/4885LY96 4436/4885LGALS8 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.