Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17054068 | 0.83 | POLB (0.47) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17427482 | 0.75 | TYRO3 (0.38) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL17427483 | 0.67 | RIPK1 (0.36) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL19980639 | 0.65 | GRM5 (0.33) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL17427475 | 0.65 | TYRO3 (0.41) | KMT2AMEN1RAB9A | |
| SCHEMBL23022737 | 0.62 | L3MBTL1 (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17409840 | 0.61 | KMT2A (0.48) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL31735702 | 0.61 | BRD4 (0.70) | — | |
| SCHEMBL21246173 | 0.61 | NR3C2 (0.35) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL24400184 | 0.61 | NTRK1 (0.48) | ALDH1A1TSHRKDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110809-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| US-9701662-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-11 | — | — | US | disclosed |
| US-9701662-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20170066745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-09 | — | — | US | disclosed |
| US-20170066745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-09 | — | — | US | disclosed |
| WO-2015128424-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066745-A1 | HERBICIDAL COMPOUNDS | DDT, HACL2, CBR3 | SMN1; SMN2 4127/4885PDE4A 925/4885PDE4B 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.