Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 10/20 | 0.40 |
| ▸ | AR | P10275 | 5/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386545 | 0.95 | ESR1 (0.45) | ESR1ESR2PGRARNR3C1 | |
| SCHEMBL21115679 | 0.87 | ESR1 (0.40) | ESR1ESR2PGRARNR3C1 | |
| SCHEMBL12990799 | 0.86 | ESR1 (0.39) | ESR1ESR2PGRARNR3C1 | |
| SCHEMBL12990387 | 0.86 | ESR1 (0.39) | ESR1ESR2PGRARNR3C1 | |
| SCHEMBL15180355 | 0.80 | ESR1 (0.35) | ESR1ESR2PGR | |
| SCHEMBL17997301 | 0.79 | S1PR5 (0.34) | ESR1ESR2PGR | |
| SCHEMBL22137718 | 0.75 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL14277901 | 0.75 | APP (0.36) | — | |
| SCHEMBL783930 | 0.74 | ESR1 (0.54) | ESR1ESR2PGRARNR3C1 | |
| SCHEMBL15257906 | 0.73 | HPGD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12043783-B2 | Liquid crystal composition containing benzochromene compound and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2024-07-23 | — | — | US | disclosed |
| US-20240067879-A1 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11873438-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-01-16 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-20230357637-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-09 | — | — | US | disclosed |
| US-11802243-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-31 | — | — | US | disclosed |
| WO-2009115186-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2009-09-24 | — | — | WO | disclosed |
| US-7582337-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-09-01 | — | — | US | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090103011-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20080197319-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080191166-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080191167-A1 | Liquid-crystalline medium | MERCK PATENT GMBH | 2008-08-14 | — | — | US | disclosed |
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-26 | — | — | US | disclosed |
| US-20080090026-A1 | Liquid-crystal display | MERCK PATENT GMBH | 2008-04-17 | — | — | US | disclosed |
| WO-2008009417-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | ESR1 3154/4885ESR2 3395/4885PGR 4633/4885 |
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | SBDS, LSS, VCL | ESR1 491/4885ESR2 1012/4885PGR 4312/4885 |
| US-20080090026-A1 | Liquid-crystal display | KLK3, LPXN, BPHL | ESR1 2370/4885ESR2 3823/4885PGR 2113/4885 |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | VCL, LCP1, LPXN | ESR1 606/4885ESR2 2083/4885PGR 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.