Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | EGFR | P00533 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.59 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144540 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL17610618 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL25736023 | 0.90 | ALDH1A1 (0.82) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL10144267 | 0.83 | ALDH1A1 (0.71) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL13060204 | 0.82 | ALDH1A1 (0.74) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL25737631 | 0.81 | EGFR (1.00) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL28509763 | 0.80 | KMT2A (0.67) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL9539321 | 0.80 | KDM4E (0.71) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| SCHEMBL9539318 | 0.80 | KDM4E (0.71) | ALDH1A1EGFRMEN1KMT2AHPGD | |
| Tyrphostin 51 SCHEMBL241622 | 0.77 | EGFR (0.80) | ALDH1A1EGFRMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156775-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2006-05-17 | — | — | EP | claimed |
| US-6121269-A | TOPICALLY APPLYING A PROTEIN-TYROSINE KINASE INHIBITOR TO SKIN TO REDUCE ANDROGEN-STIMULATED HAIR GROWTH WITHOUT SIDE EFFECTS | GILLETTE COMPANY, THE, A DELAWARE CORPORATION | 2000-09-19 | — | — | US | claimed |
| US-11406709-B2 | Therapeutic and research application of PDCL3 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-08-09 | — | — | US | disclosed |
| US-20170274075-A1 | THERAPEUTIC AND RESEARCH APPLICATION OF PDCL3 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2016044219-A1 | THERAPEUTIC AND RESEARCH APPLICATION OF PDCL3 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2016-03-24 | — | — | WO | disclosed |
| EP-2097059-B1 | CLEANSING OR CARE PRODUCT | HENKEL KGAA (DE) | 2012-04-18 | — | — | EP | disclosed |
| EP-2167017-A2 | COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HAVING A HYDROGEL FORMER | Henkel AG & Co. KGaA (DE) | 2010-03-31 | — | — | EP | disclosed |
| EP-2167018-A2 | COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION | Henkel AG & Co. KGaA (DE) | 2010-03-31 | — | — | EP | disclosed |
| US-20100047296-A1 | Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III | HENKEL AG & CO. KGAA (DE) | 2010-02-25 | — | — | US | disclosed |
| EP-2097059-A1 | CLEANSING OR CARE PRODUCT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2009-09-09 | — | — | EP | disclosed |
| US-20090220444-A1 | Antiperspirant and Deodorant Compositions with Improved Protective Action | HENKEL AG & CO. KGAA (DE) | 2009-09-03 | — | — | US | disclosed |
| WO-2008065072-A1 | CLEANSING OR CARE PRODUCT | HENKEL AG & CO. KGAA (DE) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008058943-A2 | LOW-RESIDUE COSMETIC OR DERMATOLOGICAL STICK BASED ON AN OIL-IN-WATER DISPERSION/EMULSION III | HENKEL AG & CO. KGAA (DE) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008025698-A1 | ANTIPERSPIRANT AND DEODORANT COMPOSITIONS WITH IMPROVED CARE EFFECT | HENKEL AG & CO. KGAA (DE) | 2008-03-06 | — | — | WO | disclosed |
| EP-1813310-A2 | Cosmetic stick based on an oil in water dispersion/emulsion | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1803660-A1 | Emulsion spray | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-07-04 | — | — | EP | disclosed |
| EP-1156775-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1156775-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6121269-A | TOPICALLY APPLYING A PROTEIN-TYROSINE KINASE INHIBITOR TO SKIN TO REDUCE ANDROGEN-STIMULATED HAIR GROWTH WITHOUT SIDE EFFECTS | GILLETTE COMPANY, THE, A DELAWARE CORPORATION | 2000-09-19 | — | — | US | disclosed |
| WO-2000050002-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047296-A1 | Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III | TYR, POLR1C, CUTA | ALDH1A1 1276/4885EGFR 1891/4885MEN1 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.