Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21989916 | 0.84 | VNN1 (0.46) | VNN1 | |
| SCHEMBL21989894 | 0.84 | VNN1 (0.46) | VNN1 | |
| SCHEMBL22031924 | 0.84 | VNN1 (0.46) | VNN1 | |
| SCHEMBL24597150 | 0.82 | SMN1; SMN2 (0.48) | VNN1SMN1; SMN2 | |
| SCHEMBL21112193 | 0.82 | VNN1 (0.38) | VNN1SMN1; SMN2 | |
| SCHEMBL1290638 | 0.78 | VNN1 (0.39) | VNN1 | |
| SCHEMBL22900030 | 0.77 | ALDH1A1 (0.57) | VNN1 | |
| SCHEMBL20788762 | 0.74 | DPP4 (0.34) | — | |
| SCHEMBL11198809 | 0.73 | — | — | |
| SCHEMBL22801419 | 0.72 | POLB (0.45) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440558-A1 | DIHYDROPYRROLONAPHTYRIDINONE COMPOUNDS AS INHIBITORS OF JAK | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144486-A1 | DIHYDROPYRROLONAPHTYRIDINONE COMPOUNDS AS INHIBITORS OF JAK | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |