Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.65 |
| ▸ | ACACA | Q13085 | 2/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.50 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (23E)-Cyclosadol SCHEMBL13420421 | 0.83 | ACLY (0.64) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| (23E)-Cyclosadol SCHEMBL13644394 | 0.83 | ACLY (0.64) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| (23E)-Cyclosadol SCHEMBL29636856 | 0.83 | ACLY (0.64) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| Vaticinone SCHEMBL29670808 | 0.82 | HSD11B1 (0.60) | ACLYACACAPTPN11HSD11B1PTGS1 | |
| SCHEMBL13420264 | 0.81 | ACLY (0.73) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| Cycloartenol SCHEMBL23754759 | 0.80 | ACLY (0.81) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| Cycloartenol SCHEMBL13420259 | 0.80 | ACLY (0.81) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| Cycloartenol SCHEMBL20778271 | 0.80 | ACLY (0.81) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| Cycloartenol SCHEMBL21754440 | 0.80 | ACLY (0.81) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| Cycloartenol SCHEMBL12368108 | 0.80 | ACLY (0.81) | ACLYACACAPTPN11HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568862-B2 | Xanthone-rich plant extracts or compounds therefrom for modulating diseases of the central nervous system and related disorders | DEAKIN UNIVERSITY (AU) | 2020-02-25 | — | — | US | disclosed |
| US-20160367521-A1 | XANTHONE-RICH PLANT EXTRACTS OR COMPOUNDS THEREFROM FOR MODULATING DISEASES OF THE CENTRAL NERVOUS SYSTEM AND RELATED DISORDERS | DEAKIN UNIVERSITY (AU) | 2016-12-22 | — | — | US | disclosed |
| US-20160367521-A1 | XANTHONE-RICH PLANT EXTRACTS OR COMPOUNDS THEREFROM FOR MODULATING DISEASES OF THE CENTRAL NERVOUS SYSTEM AND RELATED DISORDERS | DEAKIN UNIVERSITY (AU) | 2016-12-22 | — | — | US | disclosed |
| WO-2015127512-A1 | XANTHONE-RICH PLANT EXTRACTS OR COMPOUNDS THEREFROM FOR MODULATING DISEASES OF THE CENTRAL NERVOUS SYSTEM AND RELATED DISORDERS | DEAKIN UNIVERSITY (AU) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10568862-B2 | Xanthone-rich plant extracts or compounds therefrom for modulating diseases of the central nervous system and related disorders | GAP43, PMP22, ACHE | ACLY 2687/4885ACACA 2312/4885PTPN11 1035/4885 |
| US-20160367521-A1 | XANTHONE-RICH PLANT EXTRACTS OR COMPOUNDS THEREFROM FOR MODULATING DISEASES OF THE CENTRAL NERVOUS SYSTEM AND RELATED DISORDERS | GAP43, PMP22, ACHE | ACLY 2687/4885ACACA 2312/4885PTPN11 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.