SCHEMBL17057218

SCHEMBL17057218

c1ccc(-c2ccc(-c3cccc(-c4cc(-c5ccc6c7ccccc7c7ccccc7c6c5)cc5c4oc4ccccc45)c3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.49
▸ PLA2G2A P14555 5/20 0.44
▸ PLA2G4A P47712 5/20 0.44
▸ PLA2G10 O15496 1/20 0.44
▸ GGPS1 O95749 1/20 0.39
▸ PRKDC P78527 3/20 0.39
▸ AHR P35869 2/20 0.39
▸ PTGES2 Q9H7Z7 1/20 0.37
▸ HPGD P15428 2/20 0.36
▸ PIM1 P11309 1/20 0.36
▸ CSNK2A2 P19784 1/20 0.36
▸ CSNK2B P67870 1/20 0.36
▸ PIM3 Q86V86 1/20 0.36
▸ PIM2 Q9P1W9 1/20 0.36
▸ GABRP O00591 1/20 0.36
▸ GABRD O14764 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ CA12 O43570 1/20 0.36
▸ TNKS O95271 1/20 0.36
▸ CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25140415 1.00 ALOX5 (0.49) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL17057216 1.00 ALOX5 (0.49) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL17263360 1.00 ALOX5 (0.49) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL17057168 0.96 ALOX5 (0.52) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL24171967 0.93 ALOX5 (0.48) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL10443023 0.91 ALOX5 (0.46) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL10443173 0.91 ALOX5 (0.46) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL10442594 0.91 ALOX5 (0.46) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL18961002 0.90 ALOX5 (0.61) ALOX5PLA2G2APLA2G4APLA2G10GGPS1
SCHEMBL17425769 0.89 ALOX5 (0.56) ALOX5PLA2G2APLA2G4APLA2G10GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9190620-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 — — US disclosed
US-20150249221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150249221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, TERF2, DBF4 ALOX5 791/4885PLA2G2A 2293/4885PLA2G4A 2817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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