Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058211 | 0.88 | SLC2A1 (0.30) | SLC2A1SLC2A3POLBCYP3A4CYP2C19 | |
| SCHEMBL17058519 | 0.88 | SLC2A1 (0.32) | SLC2A1SLC2A3POLBCYP3A4CYP2C19 | |
| SCHEMBL11945886 | 0.84 | MAPT (0.36) | SLC2A1SLC2A3THRBALDH1A1KDM4E | |
| SCHEMBL17058586 | 0.81 | SMN1; SMN2 (0.35) | SLC2A1SLC2A3ALDH1A1KDM4EPOLB | |
| SCHEMBL17058475 | 0.81 | — | — | |
| SCHEMBL17057853 | 0.81 | SMN1; SMN2 (0.35) | SLC2A1SLC2A3ALDH1A1KDM4EPOLB | |
| SCHEMBL17058242 | 0.80 | HTR1A (0.32) | SMN1; SMN2 | |
| SCHEMBL17058526 | 0.78 | LIN28A (0.34) | ALDH1A1KDM4EPOLBCYP3A4CYP2C19 | |
| SCHEMBL17058238 | 0.78 | SMN1; SMN2 (0.35) | ALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL17057972 | 0.78 | POLB (0.33) | SLC2A1SLC2A3ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137179-B1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-09-02 | — | — | EP | disclosed |