SCHEMBL17059023

SCHEMBL17059023

Cc1cc(-c2ccc(C#N)cc2)c(C)cc1COC=O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PTGER4 P35408 1/20 0.37
▸ CYP11B2 P19099 2/20 0.36
▸ KDM1A O60341 4/20 0.35
▸ MMP2 P08253 2/20 0.34
▸ MMP3 P08254 2/20 0.34
▸ SRC P12931 1/20 0.34
▸ EGLN1 Q9GZT9 1/20 0.34
▸ HRH2 P25021 1/20 0.33
▸ HRH1 P35367 1/20 0.33
▸ AR P10275 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ FNTA P49354 1/20 0.33
▸ FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22298177 0.80 SRC (0.38) PTGER4SRCARALDH1A1
SCHEMBL14524914 0.78 AR (0.44) PTGER4CYP11B2KDM1AMMP3AR
SCHEMBL14525308 0.74 AR (0.38) PTGER4CYP11B2KDM1AMMP2MMP3
SCHEMBL16920311 0.71 MMP3 (0.47) MMP2MMP3
SCHEMBL16615592 0.70 HRH2 (0.42) PTGER4CYP11B2KDM1AMMP2MMP3
SCHEMBL23958923 0.70 MAOB (0.43) CYP11B2MMP3EGLN1ALDH1A1ATM
SCHEMBL134950 0.69 MAOB (0.47) CYP11B2
SCHEMBL14499523 0.69 KDM1A (0.45) CYP11B2KDM1AARALDH1A1
SCHEMBL5544383 0.69 STS (0.35) SRCFNTAFNTB
SCHEMBL16615488 0.69 MMP2 (0.40) PTGER4CYP11B2KDM1AMMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500790-B2 Optical film, circularly polarizing plate, and image display device Konica Minolta, Inc. (JP) 2016-11-22 — — US disclosed
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE SUN2, HTR3D, CRY1 PTGER4 1632/4885CYP11B2 2156/4885KDM1A 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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