SCHEMBL1706106

SCHEMBL1706106

CCC(NCc1ccccc1)O[Si](CCCN)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 7/20 0.39
SIGMAR1 Q99720 1/20 0.35
CASR P41180 1/20 0.33
MAOA P21397 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28644165 0.90 TLR2 (0.39) TLR2SIGMAR1CASRMAOA
SCHEMBL28879252 0.79
SCHEMBL21060561 0.75 MEN1 (0.42) TLR2SIGMAR1MAOAMEN1KMT2A
SCHEMBL11792666 0.72 SIGMAR1 (0.48) SIGMAR1CASRMEN1KMT2AL3MBTL1
SCHEMBL613426 0.72 ALDH1A1 (0.42) SIGMAR1MAOA
SCHEMBL9818018 0.72 TLR2 (0.36) TLR2SIGMAR1CASRL3MBTL1
SCHEMBL3409956 0.72 MEN1 (0.37) TLR2SIGMAR1MAOAMEN1KMT2A
SCHEMBL29029448 0.71 CASR (0.43) SIGMAR1CASRMEN1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL21816641 0.71 ALDH1A1 (0.41) SIGMAR1MAOA
Hydrochloric Acid SCHEMBL28376692 0.71 MEN1 (0.36) TLR2SIGMAR1MAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440604-A1 MULTILAYER SURFACE COATING WITH BARRIER LAYER Tarkett G.D.L. S.a. (LU) 2012-04-18 EP disclosed
WO-2010142325-A1 MULTILAYER SURFACE COATING WITH BARRIER LAYER TARKETT G.D.L. S.A. (LU) 2010-12-16 WO disclosed