Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 8/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706266 | 1.00 | MAPT (0.65) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| SCHEMBL1706268 | 1.00 | MAPT (0.65) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| Hydrochloric Acid SCHEMBL16776633 | 0.98 | MAPT (0.63) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| SCHEMBL29758021 | 0.88 | MAPT (0.57) | MAPTKMT2AKCNN4 | |
| SCHEMBL59841 | 0.84 | CYP1A2 (0.58) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| SCHEMBL5181868 | 0.84 | MAPT (0.56) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| SCHEMBL222049 | 0.84 | CYP1A2 (0.58) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| SCHEMBL220775 | 0.84 | CYP1A2 (0.58) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| Hydrochloric Acid SCHEMBL304449 | 0.82 | CYP1A2 (0.56) | MAPTKMT2ACYP1A2CYP2D6KCNN4 | |
| Hydrochloric Acid SCHEMBL1455022 | 0.82 | CYP1A2 (0.56) | MAPTKMT2ACYP1A2CYP2D6KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238137-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2010-10-13 | — | — | EP | claimed |
| WO-2009097287-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-06 | — | — | WO | claimed |
| EP-1426356-B1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MIRTAZAPINE AND THE PRODUCTION METHODS THEREOF | MEDICHEM SA (ES) | 2008-04-16 | — | — | EP | claimed |
| US-7265223-B2 | Intermediate compounds for the preparation of mirtazapine and production methods thereof | MEDICHEM, S.A. (ES) | 2007-09-04 | — | — | US | claimed |
| US-20040236107-A1 | Intermediate compounds for the preparation of mirtazapine and the production methods thereof | MEDICHEM, S.A. (ES) | 2004-11-25 | — | — | US | claimed |
| EP-1426356-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MIRTAZAPINE AND THE PRODUCTION METHODS THEREOF | Medichem S.A. (ES) | 2004-06-09 | — | — | EP | claimed |
| CN-86105641-A | The method for preparing antianaphylaxis and antibronchospasm of N-dibenzyl-diazacyclo alkyl-alkyl-anilide | — | 1987-04-01 | — | — | CN | claimed |
| CN-114787135-A | Substituted imidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |
| EP-3917627-A1 | ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160134-A1 | ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| CN-105813653-B | Methylene carbamate linkers for use with target-drug conjugates | 西雅图基因公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-105732414-B | The method of control of amide derivatives, the noxious organism control agent containing the amide derivatives and harmful organism | 三井化学AGRO株式会社 | 2019-05-03 | — | — | CN | disclosed |
| CN-109689111-A | Pyrrolobenzodiazepines * prodrug and its antibody conjugates | 基因泰克公司 | 2019-04-26 | — | — | CN | disclosed |
| EP-0915858-A1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | Rhone Poulenc Agro (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003490-A1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | RHONE POULENC AGRO (FR) | 1998-01-29 | — | — | WO | disclosed |
| US-5470717-A | Method for the preparation of certain β-lactam antibiotics | GIST-BROCADES N.V. (NL) | 1995-11-28 | — | — | US | disclosed |
| EP-0618979-A1 | AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN $g(b)-LACTAM ANTIBIOTICS | GIST-BROCADES B.V. (NL) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993012250-A1 | AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN β-LACTAM ANTIBIOTICS | NOVO NORDISK A/S (DK) | 1993-06-24 | — | — | WO | disclosed |
| CN-1011784-B | Process for preparing antiallergic and antimuscotromospasm agents N-benzhydryldiazacycloalkylalkyl anilides | RECKORDATY CHEMICALS CORP (CH) | 1991-02-27 | — | — | CN | disclosed |
| CN-86105641-A | The method for preparing antianaphylaxis and antibronchospasm of N-dibenzyl-diazacyclo alkyl-alkyl-anilide | — | 1987-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236107-A1 | Intermediate compounds for the preparation of mirtazapine and the production methods thereof | IMPDH1, MRM1, IMPDH2 | MAPT 2436/4885KMT2A 2004/4885CYP1A2 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.