Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 14/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707135 | 0.87 | FPR2 (0.59) | FPR2HCRTR2HCRTR1RXRARXRB | |
| SCHEMBL1706912 | 0.80 | FPR2 (0.52) | FPR2RXRARXRBRXRGNR4A2 | |
| SCHEMBL1166789 | 0.79 | FPR2 (0.49) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL1706196 | 0.76 | FPR2 (0.42) | FPR2HCRTR2HCRTR1RXRARXRB | |
| SCHEMBL1705891 | 0.76 | FPR2 (0.54) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL1166697 | 0.76 | HCRTR2 (0.61) | HCRTR2HCRTR1 | |
| SCHEMBL1705849 | 0.73 | FPR2 (0.56) | FPR2HCRTR2 | |
| SCHEMBL9926029 | 0.73 | FPR2 (0.77) | FPR2 | |
| SCHEMBL1706330 | 0.71 | FPR2 (0.52) | FPR2HCRTR2 | |
| SCHEMBL9900336 | 0.70 | FPR2 (1.00) | FPR2HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440536-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-04-18 | — | — | EP | claimed |
| EP-2440536-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-04-18 | — | — | EP | disclosed |