Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064825 | 0.83 | KLKB1 (0.37) | PARP1 | |
| SCHEMBL17064978 | 0.81 | KLKB1 (0.39) | PARP1 | |
| SCHEMBL17064373 | 0.81 | AURKA (0.33) | — | |
| SCHEMBL17064524 | 0.77 | SLC6A2 (0.40) | KCNH2 | |
| SCHEMBL17064816 | 0.74 | HRH1 (0.40) | — | |
| SCHEMBL17064553 | 0.72 | TBXAS1 (0.36) | KCNH2 | |
| SCHEMBL17064743 | 0.69 | KLKB1 (0.33) | — | |
| SCHEMBL25805122 | 0.69 | — | — | |
| SCHEMBL17064475 | 0.69 | ADRB1 (0.35) | — | |
| SCHEMBL17064372 | 0.66 | KLKB1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113772-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134998-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2015-09-11 | — | — | WO | disclosed |