Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705486 | 0.76 | TERT (0.46) | ALOX15TBXAS1HTR2BTERTTAAR1 | |
| SCHEMBL8068830 | 0.71 | TERT (0.42) | ALOX15TBXAS1TERTTAAR1FDPS | |
| SCHEMBL8572531 | 0.70 | HRH3 (0.49) | ALOX15TBXAS1TERTTAAR1FDPS | |
| SCHEMBL2333857 | 0.70 | ALOX15 (0.42) | ALOX15HTR2BPDE5ATAAR1HTR1A | |
| SCHEMBL17500052 | 0.68 | ALOX15 (0.46) | ALOX15TBXAS1TERTPDE5ATAAR1 | |
| SCHEMBL285224 | 0.67 | TERT (0.59) | ALOX15TBXAS1TERTTAAR1HTR1A | |
| SCHEMBL16219828 | 0.66 | BRD4 (0.42) | — | |
| SCHEMBL1706497 | 0.66 | NPC1 (0.36) | ALOX15ALDH1A1 | |
| SCHEMBL8203376 | 0.65 | TBXAS1 (0.50) | ALOX15TBXAS1HTR2BTERTTAAR1 | |
| SCHEMBL2148633 | 0.64 | TAAR1 (0.49) | ALOX15TBXAS1TERTTAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440519-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-04-18 | — | — | EP | claimed |
| WO-2010144371-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-12-16 | — | — | WO | claimed |