SCHEMBL17065711

SCHEMBL17065711

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nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
LMNA P02545 2/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
KDM4E B2RXH2 2/20 0.44
PDE4A P27815 1/20 0.44
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
ALDH1A1 P00352 1/20 0.38
MGAM O43451 5/20 0.33
MAPT P10636 1/20 0.32
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18210866 1.00 TDP1 (0.71) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL29981733 1.00 TDP1 (0.71) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL8854310 0.97 LMNA (0.69) TDP1LMNAL3MBTL1KDM4EPDE4A
Perseitol SCHEMBL9231331 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A
Perseitol SCHEMBL20567548 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A
Perseitol SCHEMBL23832483 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL12344326 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL22283330 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A
Perseitol SCHEMBL6078811 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A
Perseitol SCHEMBL6078816 0.84 TDP1 (1.00) TDP1LMNAL3MBTL1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586135-A Biomass-based surfactant thickener and preparation method thereof 中国科学院化学研究所 2024-02-23 CN claimed
CN-117586135-A Biomass-based surfactant thickener and preparation method thereof 中国科学院化学研究所 2024-02-23 CN disclosed
US-20190144411-A1 Process for the preparation of (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl) methyl]phenyl]-D-glucitol and its solvate thereof MSN LABORATORIES PRIVATE LIMITED (IN) 2019-05-16 US disclosed
US-20170029398-A1 PROCESS FOR THE PREPARATION OF (1S)-1,5-ANHYDRO-1-C-{4-CHLORO-3-4[(4-ETHOXYPHENYL)METHYL]PHENYL]-GLUCITOL AND ITS SOLVATE THEREOF MSN LABORATORIES PRIVATE LIMITED (IN) 2017-02-02 US disclosed
EP-3114115-A2 PROCESS FOR THE PREPARATION OF (1S)-1,5-ANHYDRO-1-C-[4-CHLORO-3-[(4-ETHOXYPHENYL)METHYL]PHENYL]-D-GLUCITOL AND ITS SOLVATE THEREOF MSN Laboratories Private Limited (IN) 2017-01-11 EP disclosed
WO-2015132803-A2 PROCESS FOR THE PREPARATION OF (1S)-1,5-ANHYDRO-1-C-[4-CHLORO-3-[(4-ETHOXYPHENYL)METHYL]PHENYL]-D-GLUCITOL AND ITS SOLVATE THEREOF MSN LABORATORIES PRIVATE LIMITED (IN) 2015-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170029398-A1 PROCESS FOR THE PREPARATION OF (1S)-1,5-ANHYDRO-1-C-{4-CHLORO-3-4[(4-ETHOXYPHENYL)METHYL]PHENYL]-GLUCITOL AND ITS SOLVATE THEREOF ADH1C, ALG1, UGGT1 TDP1 1109/4885LMNA 2241/4885L3MBTL1 2150/4885
US-20190144411-A1 Process for the preparation of (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl) methyl]phenyl]-D-glucitol and its solvate thereof ADH1C, ALG1, UGGT1 TDP1 983/4885LMNA 2041/4885L3MBTL1 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.