Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065809 | 0.86 | KDM4E (0.50) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17065833 | 0.73 | HPGD (0.44) | L3MBTL1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL5752191 | 0.72 | CYP2A6 (0.48) | MEN1KMT2AKDM4ERAB9AMAPT | |
| SCHEMBL15266968 | 0.72 | CYP1A2 (0.48) | MEN1KMT2AKDM4EDYRK1AMAPT | |
| SCHEMBL5337507 | 0.70 | TUBB4A (0.50) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL27902298 | 0.70 | CYP2A6 (0.65) | MEN1KMT2AKDM4EALDH1A1MAPK1 | |
| SCHEMBL6959555 | 0.69 | KDM4E (0.56) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17065823 | 0.69 | NPSR1 (0.44) | ACHEL3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL11786558 | 0.69 | DYRK1A (0.55) | ACHEMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3137389 | 0.68 | CYP2A6 (0.62) | MEN1KMT2AKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113768-A1 | USE OF ARYLALKANOLAMINES AS SIGMA-1 RECEPTOR ANTAGONISTS | Universita' Degli Studi Di Pavia (IT) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015132733-A1 | USE OF ARYLALKANOLAMINES AS SIGMA-1 RECEPTOR ANTAGONISTS | UNIVERSITA' DEGLI STUDI DI PAVIA (IT) | 2015-09-11 | — | — | WO | disclosed |