Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066287 | 0.98 | NPC1 (0.46) | KIF11NPC1RAB9AXDHHDAC6 | |
| SCHEMBL14421616 | 0.84 | KMT2A (0.41) | NPC1RAB9ANISCHALDH1A1HPGD | |
| SCHEMBL2617474 | 0.82 | NPC1 (0.40) | NPC1RAB9AXDHADORA2AALDH1A1 | |
| SCHEMBL14531238 | 0.82 | ADORA3 (0.33) | NPC1RAB9AADORA2A | |
| SCHEMBL14417664 | 0.82 | METAP2 (0.38) | NPC1RAB9AADORA2A | |
| SCHEMBL1690213 | 0.81 | ADORA1 (0.47) | RAB9AADORA2ACLK2DYRK1ACLK4 | |
| SCHEMBL2104701 | 0.79 | ADORA3 (0.33) | ADORA2A | |
| SCHEMBL2104139 | 0.78 | ALDH1A1 (0.35) | KIF11ADORA2AALDH1A1MAPTNPSR1 | |
| SCHEMBL2570966 | 0.76 | NPC1 (0.42) | NPC1RAB9AHPGDNOTUM | |
| SCHEMBL1690338 | 0.76 | MAPK1 (0.45) | CLK2HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125904-B1 | Biphenyl imidazoles and related compounds useful for treating HCV infections | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-08 | — | — | US | disclosed |