Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18237855 | 0.83 | SLC6A4 (0.43) | SLC6A4SLC6A2CYP2D6SLC6A3HTR2C | |
| SCHEMBL17066197 | 0.76 | HTR2C (0.39) | SLC6A4SLC6A2CYP2D6SLC6A3HTR2C | |
| SCHEMBL17066444 | 0.74 | SLC6A4 (0.43) | SLC6A4SLC6A2CYP2D6SLC6A3HTR2C | |
| SCHEMBL18250386 | 0.62 | HTR2A (0.37) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL17066196 | 0.62 | HTR2A (0.40) | HTR2CHTR2AMEN1KMT2AHTR2B | |
| SCHEMBL18250387 | 0.61 | HTR2A (0.35) | SLC6A4SLC6A2CYP2D6SLC6A3HTR2C | |
| SCHEMBL19831763 | 0.60 | ADRA2A (0.53) | SLC6A4SLC6A2CYP2D6SLC6A3 | |
| SCHEMBL14568476 | 0.60 | HTR2C (0.59) | SLC6A4SLC6A2CYP2D6HTR2CHTR2A | |
| SCHEMBL13050996 | 0.59 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL13051002 | 0.59 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125866-B1 | Antidepressant compounds | KING SAUD UNIVERSITY (SA) | 2015-09-08 | — | — | US | disclosed |