SCHEMBL1706652

SCHEMBL1706652

CC(C)(Br)C(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
TDP1 Q9NUW8 3/20 0.53
KMT2A Q03164 2/20 0.53
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
LMNA P02545 2/20 0.49
HCAR2 Q8TDS4 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 1/20 0.48
TSHR P16473 2/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
MAOB P27338 1/20 0.46
PTPRC P08575 1/20 0.46
PTPN1 P18031 1/20 0.46
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991531 0.86 ALDH1A1 (0.62) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL522510 0.86 ALDH1A1 (0.62) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL7483779 0.85 ALDH1A1 (0.56) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL28246707 0.85 ALDH1A1 (0.60) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
Ammonia Solution, Strong SCHEMBL27451848 0.85 ALDH1A1 (0.60) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL24347012 0.85 ALDH1A1 (0.60) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL3756497 0.85 ALDH1A1 (0.60) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL9579513 0.84 ALDH1A1 (0.59) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL7636130 0.84 ALDH1A1 (0.59) ALDH1A1TDP1KMT2AMAPK1L3MBTL1
SCHEMBL25946864 0.84 RXRA (0.53) ALDH1A1KMT2ASMN1; SMN2MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129416-B1 REGULATION OF A CONTROLLED RADICAL POLYMERIZATION OF ACRYLATES BY LIGHT DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-06 EP claimed
EP-3129416-A1 REGULATION OF A CONTROLLED RADICAL POLYMERIZATION OF ACRYLATES BY LIGHT Dow Global Technologies LLC (US) 2017-02-15 EP claimed
US-20170029535-A1 REGULATION OF A CONTROLLED RADICAL POLYMERIZATION OF ACRYLATES BY LIGHT DOW GLOBAL TECHNOLOGIES LLC 2017-02-02 US claimed
WO-2015157149-A1 REGULATION OF A CONTROLLED RADICAL POLYMERIZATION OF ACRYLATES BY LIGHT DOW GLOBAL TECHNOLOGIES LLC (US) 2015-10-15 WO claimed
EP-4594380-A1 POLYMERS Molecular Medical Ltd (GB) 2025-08-06 EP disclosed
WO-2024069162-A1 POLYMERS MOLECULAR MEDICAL LTD (GB) 2024-04-04 WO disclosed
CN-117777856-A Photocurable release agent and low-roughness high-uniformity MLCC release film 扬州万润光电科技股份有限公司 2024-03-29 CN disclosed
WO-2022146360-A2 REDUCED GRAPHENE OXIDE (rGO) BASED DRUG CARRIER SYSTEMS ISTANBUL MEDIPOL UNIVERSITESI TEKNOLOJI TRANSFER OFISI ANONIM SIRKETI (TR) 2022-07-07 WO disclosed
EP-3271155-B1 METHOD OF ADDITIVE MANUFACTURING USING PHOTOREGULATED RADICAL POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-30 EP disclosed
US-10647056-B2 Method of additive manufacturing using photoregulated radical polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-12 US disclosed
EP-3625320-A1 COMPOSITION Unilever PLC (GB) 2020-03-25 EP disclosed
WO-2018210700-A1 COMPOSITION UNILEVER PLC (GB) 2018-11-22 WO disclosed
EP-1007505-A1 CERTAIN 5-ALKYL-2-ARYLAMINOPHENYLACETIC ACIDS AND DERIVATIVES Novartis AG (CH) 2000-06-14 EP disclosed
WO-1999011605-A1 CERTAIN 5-ALKYL-2-ARYLAMINOPHENYLACETIC ACIDS AND DERIVATIVES NOVARTIS AG (CH) 1999-03-11 WO disclosed
CN-1148393-A Bradykinin antagonist peptides incorporating N-substituted glycines CORTECH INC (US) 1997-04-23 CN disclosed
US-4472380-A CARBOXYALKYL DIPEPTIDE DERIVATIVES MERCK & CO., INC. (US) 1984-09-18 US disclosed
EP-0027948-B1 TETRAHYDRO-FLUORENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF MERCK & CO. INC. (US) 1984-03-21 EP disclosed
US-4374829-A Aminoacid derivatives as antihypertensives MERCK & CO., INC. (US) 1983-02-22 US disclosed
EP-0027948-A1 Tetrahydro-fluorene compounds, processes for their preparation and pharmaceutical compositions thereof MERCK & CO. INC. (US) 1981-05-06 EP disclosed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 EP disclosed