Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24347012 | 0.89 | ALDH1A1 (0.60) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL522510 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL991531 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL30441478 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8580399 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL15114664 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL1706652 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27451848 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28246707 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL2032918 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577325-B2 | Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof | SYSTIMMUNE, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4595978-A1 | ANTI-CD33 ANTIBODY AND ANTI-CD33 ANTIBODY-DRUG CONJUGATE AND USE THEREOF | SystImmune, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| CN-120131991-A | Anti-human Claudin18.2 antibody-camptothecine drug conjugate and medical application thereof | 成都百利多特生物药业有限责任公司 | 2025-06-13 | — | — | CN | disclosed |
| US-20250115679-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. (CN) | 2025-04-10 | — | — | US | disclosed |
| US-20250059296-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | SYSTIMMUNE INC (US) | 2025-02-20 | — | — | US | disclosed |
| CN-117752813-A | anti-CD 33 antibodies and anti-CD 33 antibody-drug conjugates and uses thereof | 成都百利多特生物药业有限责任公司 | 2024-03-26 | — | — | CN | disclosed |
| US-11912686-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230226207-A1 | Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof | SYSTIMMUNE, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230226207-A1 | Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof | SYSTIMMUNE, INC. | 2023-07-20 | — | — | US | disclosed |
| US-11702407-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20080009474-A1 | PENEM PRODRUGS | PFIZER INC | 2008-01-10 | — | — | US | disclosed |
| WO-2008001212-A2 | PENEM PRODRUGS | PFIZER PRODUCTS INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5348953-A | Elastase inhibitor | MERCK & CO., INC. (US) | 1994-09-20 | — | — | US | disclosed |
| WO-1994013636-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| CN-1068815-A | Be used as the new substituted azetidinone of anti-inflammatory and antidegenerative agent | MERCK & CO INC (US) | 1993-02-10 | — | — | CN | disclosed |
| EP-0525973-A2 | Substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993000332-A1 | SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702407-B2 | LPA receptor antagonists and uses thereof | LPAR1, LPAR2, LPAR4 | ALDH1A1 1727/4885TDP1 3649/4885KMT2A 2867/4885 |
| US-12577325-B2 | Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof | IGLV6-57, EGFR, ERBB2 | ALDH1A1 3799/4885TDP1 1675/4885KMT2A 2519/4885 |
| US-20250115679-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | ANTXR2, PAICS, CD38 | ALDH1A1 1919/4885TDP1 3050/4885KMT2A 3730/4885 |
| US-20080009474-A1 | PENEM PRODRUGS | PGM2, PGLS, PMM2 | ALDH1A1 2418/4885TDP1 4272/4885KMT2A 2221/4885 |
| US-20230226207-A1 | Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof | SLC7A1, CD44, DCLRE1A | ALDH1A1 2318/4885TDP1 2486/4885KMT2A 3696/4885 |
| US-20250059296-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | ANTXR2, PAICS, CD38 | ALDH1A1 1919/4885TDP1 3050/4885KMT2A 3730/4885 |
| US-11912686-B2 | LPA receptor antagonists and uses thereof | LPAR1, LPAR2, LPAR4 | ALDH1A1 1726/4885TDP1 4039/4885KMT2A 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.