Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13470074 | 0.91 | ALDH1A1 (0.54) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17066643 | 0.90 | TP53 (0.60) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL13470473 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ALOX12MEN1KMT2AMAPT | |
| SCHEMBL16358473 | 0.88 | TP53 (0.62) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL13453957 | 0.88 | ALDH1A1 (0.57) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL13469996 | 0.88 | ALDH1A1 (0.53) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17066552 | 0.88 | ALDH1A1 (0.56) | ALDH1A1ALOX12MEN1KMT2AMAPT | |
| SCHEMBL17066569 | 0.88 | ALDH1A1 (0.72) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17066610 | 0.88 | ALDH1A1 (0.68) | TP53ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17066675 | 0.88 | GPR55 (0.67) | TP53ALDH1A1ALOX12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |