Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453902 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTGPR55 | |
| SCHEMBL17066668 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL13470337 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPTGPR55 | |
| SCHEMBL13470089 | 0.89 | PKM (0.67) | ALDH1A1KMT2AMEN1MAPTGPR55 | |
| SCHEMBL17066566 | 0.88 | TP53 (0.59) | ALDH1A1KMT2AMEN1MAPTGPR55 | |
| SCHEMBL13470084 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL17066555 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL17066557 | 0.87 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1MAPTGPR55 | |
| SCHEMBL13453842 | 0.87 | GPR55 (0.56) | ALDH1A1KMT2AMEN1MAPTGPR55 | |
| SCHEMBL17066666 | 0.87 | GPR55 (0.71) | ALDH1A1KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |