Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GPR27 | Q9NS67 | 8/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13454757 | 0.89 | AVPR2 (0.64) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL13454759 | 0.88 | ALDH1A1 (0.67) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL13454628 | 0.87 | PKM (0.56) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL16358462 | 0.87 | GPR55 (0.67) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL12903592 | 0.86 | ALDH1A1 (0.55) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL13453739 | 0.86 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13454758 | 0.86 | ALDH1A1 (0.69) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL17066663 | 0.86 | ALDH1A1 (0.69) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL17066701 | 0.86 | GPR55 (0.66) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 | |
| SCHEMBL13453772 | 0.86 | ALDH1A1 (0.67) | GPR55ALDH1A1LMNASMN1; SMN2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |