Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TCF4 | P15884 | 2/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13469980 | 0.92 | TCF4 (0.65) | GPR55ALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17066564 | 0.90 | GPR55 (0.77) | GPR55ALDH1A1ALOX12LMNASMN1; SMN2 | |
| SCHEMBL13469988 | 0.90 | ALDH1A1 (0.63) | GPR55ALDH1A1ALOX12LMNASMN1; SMN2 | |
| SCHEMBL13470014 | 0.89 | TCF4 (0.56) | GPR55ALDH1A1ALOX12THRBMEN1 | |
| SCHEMBL13470281 | 0.88 | ALDH1A1 (0.56) | GPR55ALDH1A1ALOX12THRBMEN1 | |
| SCHEMBL13469733 | 0.88 | ALDH1A1 (0.67) | GPR55ALDH1A1ALOX12LMNASMN1; SMN2 | |
| SCHEMBL13453869 | 0.87 | ALDH1A1 (0.69) | GPR55ALDH1A1ALOX12LMNASMN1; SMN2 | |
| SCHEMBL17066704 | 0.86 | GPR55 (0.86) | GPR55ALDH1A1ALOX12LMNASMN1; SMN2 | |
| SCHEMBL13469972 | 0.86 | ALDH1A1 (0.64) | ALDH1A1ALOX12LMNASMN1; SMN2THRB | |
| SCHEMBL13453815 | 0.85 | ALDH1A1 (0.57) | ALDH1A1ALOX12LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |