Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987129 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2APGRTP53POLB | |
| SCHEMBL15730214 | 0.77 | KDM4E (0.43) | MEN1KMT2AKDM4EALOX15HSD17B10 | |
| SCHEMBL23501955 | 0.75 | PGR (0.33) | MEN1KMT2AKDM4EPGRTP53 | |
| SCHEMBL23835719 | 0.75 | PGR (0.52) | MEN1KMT2AKDM4EHSD17B10PGR | |
| SCHEMBL17066904 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AHSD17B10PGRTP53 | |
| SCHEMBL18854050 | 0.69 | PGR (0.50) | KDM4EPGRTP53POLBMAPT | |
| SCHEMBL2693278 | 0.66 | IDO1 (0.64) | KDM4EPGRMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24019919 | 0.66 | PGR (0.57) | PGRTP53POLBMAPTALDH1A1 | |
| SCHEMBL23835758 | 0.66 | PGR (0.43) | KDM4EPGRTP53POLBMAPT | |
| SCHEMBL2988866 | 0.66 | PGR (0.57) | PGRTP53POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729448-B1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES INC (US) | 2015-09-09 | — | — | EP | disclosed |