SCHEMBL1706716

SCHEMBL1706716

FC(F)(F)[C]1C=CON1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17559820 0.59
SCHEMBL405287 0.57
SCHEMBL22121184 0.43 GLA (0.31)
SCHEMBL15850523 0.43 KIF11 (0.44)
SCHEMBL6754916 0.41 POLB (0.41)
SCHEMBL63468 0.41 ALDH1A1 (0.67)
SCHEMBL10600250 0.41 NOTUM (0.30)
SCHEMBL1037620 0.38
SCHEMBL8466155 0.38
Dibromodifluoromethane SCHEMBL102197 0.38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094705-B1 AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS BRISTOL MYERS SQUIBB CO (US) 2012-04-18 EP claimed
EP-0942909-B1 BICYCLIC AMINE DERIVATIVES SYNGENTA LTD (GB) 2002-06-12 EP disclosed