SCHEMBL17067247

SCHEMBL17067247

C=C/C=C\C(\C=C\C(N)=O)=C/C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
FGFR4 P22455 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1027014 0.83 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
SCHEMBL21139376 0.80 ALDH1A1 (0.38) ALDH1A1
SCHEMBL15684690 0.80 TSHR (0.41) ALDH1A1TSHR
SCHEMBL28121781 0.79 ALDH1A1 (0.41) ALDH1A1TSHRFGFR4
SCHEMBL28942101 0.78
SCHEMBL458171 0.78
SCHEMBL177783 0.78
SCHEMBL23879511 0.77 DDAH1 (0.31) ALDH1A1TSHRFGFR4
SCHEMBL19771799 0.77
SCHEMBL9480208 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301458-B1 SYNTHESIS OF FUNCTIONALIZED AND UNFUNCTIONALIZED OLEFINS VIA CROSS AND RING-CLOSING METATHESIS CALIFORNIA INST OF TECHN (US) 2015-09-09 EP disclosed