Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 12/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141861 | 0.88 | MIF (0.77) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9610849 | 0.82 | MIF (0.63) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL8763362 | 0.81 | MIF (0.68) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL28396661 | 0.81 | IDO1 (0.44) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL436823 | 0.79 | IDO1 (0.42) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL3364900 | 0.78 | MIF (0.66) | MIFTRPA1C3AR1NAAACYP2A6 | |
| SCHEMBL19987607 | 0.77 | IDO1 (0.41) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL895951 | 0.77 | MIF (0.64) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL1457562 | 0.77 | MIF (1.00) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL17049997 | 0.77 | MIF (0.50) | MIFTRPA1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574647-A | Detection and localization of internal bleeding | 范德堡大学 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023210570-A1 | PLANT STOMATAL OPENING REGULATOR | 国立大学法人東海国立大学機構 | 2023-11-02 | — | — | WO | disclosed |
| US-10029997-B2 | Compositions and methods for treating cancers | CEDARS-SINAI MEDICAL CENTER (US) | 2018-07-24 | — | — | US | disclosed |
| US-9656991-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20170121297-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCERS | CEDARS-SINAI MEDICAL CENTER (US) | 2017-05-04 | — | — | US | disclosed |
| EP-2865670-B1 | Thiourea derivatives as glutaminyl cyclase inhibitors | PROBIODRUG AG (DE) | 2017-01-11 | — | — | EP | disclosed |
| US-20160038485-A1 | PHASE 2 INDUCERS AND RELATED SIGNALING PATHWAYS PROTECT CARTILAGE AGAINST INFLAMMATION, APOPTOSIS AND STRESS | TALALAY, PAUL | 2016-02-11 | — | — | US | disclosed |
| US-9234256-B2 | Scavenger supports and the use thereof in a process for the extraction of metals | JOHNSON MATTHEY FINLAND OY (FI) | 2016-01-12 | — | — | US | disclosed |
| US-9126987-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2015-09-08 | — | — | US | disclosed |
| EP-2865670-A1 | Thiourea derivatives as glutaminyl cyclase inhibitors | Probiodrug AG (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-6720352-B1 | HETEROCYCLIC ALDEHYDES; ISOTHIOCYANATES; FURFURAL; METHYL ISOTHIOCYANTATE; ALLYL ISOTHIOCYANATE; CROPS | ILLOVO SUGAR LIMITED (ZA) | 2004-04-13 | — | — | US | disclosed |
| CN-1443179-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2003-09-17 | — | — | CN | disclosed |
| WO-2003074515-A1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003053437-A1 | TRIAZOLES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |
| CN-1356871-A | Compositions and methods for controlling nematodes | ILLOVO SUGAR LTD (ZA) | 2002-07-03 | — | — | CN | disclosed |
| EP-1180933-A1 | COMPOSITIONS AND PROCESS FOR NEMATODE CONTROL | Illovo Sugar Limited (ZA) | 2002-02-27 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000067577-A1 | COMPOSITIONS AND PROCESS FOR NEMATODE CONTROL | ILLOVO SUGAR LIMITED (ZA) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| WO-1994026715-A1 | AMIDINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121297-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCERS | GSK3B, HDAC1, HDAC3 | MIF 1484/4885TRPA1 4733/4885ALDH1A1 766/4885 |
| US-20160038485-A1 | PHASE 2 INDUCERS AND RELATED SIGNALING PATHWAYS PROTECT CARTILAGE AGAINST INFLAMMATION, APOPTOSIS AND STRESS | PTGS2, PTGES2, CCAR2 | MIF 737/4885TRPA1 388/4885ALDH1A1 658/4885 |
| US-10029997-B2 | Compositions and methods for treating cancers | HDAC3, HDAC1, GSK3B | MIF 1150/4885TRPA1 4757/4885ALDH1A1 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.