Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 11/20 | 0.66 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.64 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.64 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332410 | 0.89 | MIF (0.79) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL18779660 | 0.85 | MIF (0.69) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL8763660 | 0.83 | MIF (0.70) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL3967224 | 0.79 | MIF (0.66) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL1457483 | 0.79 | MIF (1.00) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL2947970 | 0.79 | MIF (1.00) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL11253670 | 0.79 | CYP2A6 (0.45) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL9116288 | 0.79 | MIF (0.92) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL4701206 | 0.79 | MIF (0.68) | MIFCYP2A6TRPA1CYP2E1HIF1A | |
| SCHEMBL1706732 | 0.78 | MIF (0.63) | MIFCYP2A6TRPA1CYP2E1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303503-B1 | ANILINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-7312326-B2 | Fluorescent labeled nucleotide derivatives | BECKMAN COULTER, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7074933-B2 | Urea and thiourea derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1603882-A2 | UREA AND THIOUREA DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-12-14 | — | — | EP | disclosed |
| CN-1208329-C | Novel aniline derivative | HOFFMANN LA ROCHE (CH) | 2005-06-29 | — | — | CN | disclosed |
| US-20040266820-A1 | Urea and thiourea derivatives | DU DANIEL Y (US) | 2004-12-30 | — | — | US | disclosed |
| WO-2004072044-A2 | UREA AND THIOUREA DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-26 | — | — | WO | disclosed |
| CN-1443179-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2003-09-17 | — | — | CN | disclosed |
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266820-A1 | Urea and thiourea derivatives | SHBG, ZP1, ZYX | MIF 1412/4885CYP2A6 817/4885TRPA1 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.