Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 6/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768385 | 0.78 | FFAR1 (0.42) | FFAR1FFAR4HAO1PTGES | |
| SCHEMBL11512104 | 0.75 | NPSR1 (0.42) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL927052 | 0.75 | FFAR1 (0.58) | FFAR1FFAR4HAO1EGLN1 | |
| SCHEMBL27316970 | 0.74 | FFAR1 (0.53) | FFAR1FFAR4HAO1KMT2A | |
| SCHEMBL2465152 | 0.71 | GABRA1 (0.35) | FFAR1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL2469689 | 0.71 | CA12 (0.41) | FFAR1HAO1 | |
| SCHEMBL4607981 | 0.70 | APP (0.56) | FFAR1FFAR4HAO1TBK1MEN1 | |
| SCHEMBL18626138 | 0.69 | APP (0.52) | FFAR1FFAR4HAO1PTGESKDM4E | |
| SCHEMBL2565461 | 0.69 | APP (0.52) | FFAR1FFAR4HAO1PTGESKDM4E | |
| SCHEMBL4498928 | 0.69 | FFAR1 (0.60) | FFAR1FFAR4HAO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440519-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144371-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-12-16 | — | — | WO | disclosed |