Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702866 | 1.00 | MEP1B (0.34) | MEP1BTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1702864 | 1.00 | MEP1B (0.34) | MEP1BTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12011110 | 0.92 | MEP1B (0.34) | MEP1BTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15121780 | 0.91 | ALDH1A1 (0.36) | MEP1BTSHRKDM4EALDH1A1TAS1R3 | |
| SCHEMBL12009810 | 0.88 | MEP1B (0.32) | MEP1BTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14354266 | 0.86 | MEP1B (0.31) | MEP1BTSHRSLC6A3 | |
| SCHEMBL1706143 | 0.86 | MEP1B (0.31) | MEP1BTSHRSLC6A3 | |
| SCHEMBL1706144 | 0.86 | MEP1B (0.31) | MEP1BTSHRSLC6A3 | |
| SCHEMBL1703129 | 0.86 | TSHR (0.36) | MEP1BTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13046703 | 0.85 | MEP1B (0.35) | MEP1BTSHRKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440530-B1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2013-07-24 | — | — | EP | disclosed |
| US-8252938-B2 | Process for the preparation of 6-(aryl)-4-aminopicolinates | DOW AGROSCIENCES, LLC. (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2440530-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144380-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | HTR6, CYP46A1, NISCH | MEP1B 780/4885TSHR 2536/4885KDM4E 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.