Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.50 |
| ▸ | CES1 | P23141 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482477 | 0.86 | POLB (0.53) | CES2CES1MAPTPOLBGAA | |
| SCHEMBL11482485 | 0.86 | POLB (0.53) | CES2CES1MAPTPOLBGAA | |
| SCHEMBL11572214 | 0.86 | POLB (0.53) | CES2CES1MAPTPOLBGAA | |
| SCHEMBL9917542 | 0.78 | MAPT (0.53) | CES2CES1MAPTGAACYP2C19 | |
| SCHEMBL31621295 | 0.77 | ALDH1A1 (0.61) | CES2CES1MAPTPOLBGAA | |
| SCHEMBL8225946 | 0.76 | GAA (0.37) | MAPTPOLBGAACYP2C19TSHR | |
| Benzil SCHEMBL5372731 | 0.75 | CES2 (0.78) | CES2CES1MAPTTSHRALDH1A1 | |
| SCHEMBL4353902 | 0.74 | GAA (0.65) | CES2CES1MAPTPOLBGAA | |
| SCHEMBL12997589 | 0.74 | GAA (0.65) | CES2CES1MAPTPOLBGAA | |
| Benzil SCHEMBL9473091 | 0.73 | CES2 (0.74) | CES2CES1MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150252235-A1 | UV-CURABLE SILICONE ADHESIVE COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-10 | — | — | US | disclosed |