Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028815 | 0.93 | — | — | |
| SCHEMBL16646195 | 0.90 | GRIN2B (0.41) | GRIN2BGRIN2C | |
| SCHEMBL17030274 | 0.90 | GRIN2B (0.41) | GRIN2BGRIN2C | |
| SCHEMBL22213480 | 0.89 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL12028816 | 0.87 | SLC15A1 (0.39) | — | |
| SCHEMBL7933725 | 0.87 | CTSL (0.46) | — | |
| SCHEMBL7932040 | 0.87 | CTSL (0.46) | — | |
| SCHEMBL18538176 | 0.86 | HTT (0.37) | GRIN2BGRIN2C | |
| SCHEMBL12047518 | 0.86 | CTSL (0.41) | — | |
| SCHEMBL12028817 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593145-B2 | Secondary structure stabilized NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160115197-A1 | SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF | INNOVIVA TRC HOLDINGS LLC | 2016-04-28 | — | — | US | disclosed |
| US-20150253305-A1 | METHODS OF IDENTIFYING COMPOUNDS FOR TREATING DEPRESSION AND OTHER RELATED DISEASES | NORTHWESTERN UNIVERSITY | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115197-A1 | SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN2A, GRIN1, GRIN3A | GRIN2B 4/4885GRIN2C 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.