SCHEMBL17071920

SCHEMBL17071920

COc1ccc(-c2ccc(Cl)cc2OS(=O)(=O)C(F)(F)F)c2c(OC)cccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
PRMT1 Q99873 1/20 0.37
MEN1 O00255 1/20 0.37
NR3C1 P04150 1/20 0.37
PGR P06401 1/20 0.37
NR3C2 P08235 1/20 0.37
AR P10275 1/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HTT P42858 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
PABPC1 P11940 1/20 0.36
XBP1 P17861 1/20 0.36
NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8725902 0.81 MAPT (0.42) POLBKMT2APRMT1MEN1KDM4E
SCHEMBL12476299 0.76 MEN1 (0.41) KMT2AMEN1
SCHEMBL16376432 0.75 MEN1 (0.40) POLBKMT2AMEN1KDM4EMAPT
SCHEMBL17071921 0.75 PPARG (0.45) POLBKMT2APRMT1MEN1KDM4E
SCHEMBL17120260 0.74 MEN1 (0.36) POLBKMT2AMEN1KDM4EMAPT
SCHEMBL8636736 0.73 IDO1 (0.46) ALDH1A1NPC1FABP4
SCHEMBL5374919 0.72 PDE4A (0.44) POLBACHE
SCHEMBL6852260 0.71 MAPK1 (0.37) POLBKMT2AMEN1KDM4EMAPT
SCHEMBL17487158 0.71 ALDH1A1 (0.39) KMT2AMEN1KDM4EMAPTHSD17B10
SCHEMBL17071922 0.71 KMT2A (0.39) POLBKMT2APRMT1MEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9455407-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-27 US disclosed
US-20150255723-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMDUNG DISPLAY CO., LTD. (KR) 2015-09-10 US disclosed