Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476299 | 0.87 | MEN1 (0.41) | GAAKMT2AMEN1HTR6DRD2 | |
| SCHEMBL6852260 | 0.85 | MAPK1 (0.37) | MAPTKMT2APOLBMEN1KDM4E | |
| SCHEMBL8636736 | 0.84 | IDO1 (0.46) | ALDH1A1 | |
| SCHEMBL17487158 | 0.82 | ALDH1A1 (0.39) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17071920 | 0.81 | TRPV4 (0.37) | MAPTKMT2APOLBMEN1PRMT1 | |
| SCHEMBL18117640 | 0.79 | MAOA (0.51) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3454716 | 0.79 | DRD2 (0.38) | GAAKMT2AMEN1DRD2HTR1D | |
| SCHEMBL5599606 | 0.79 | CA1 (0.50) | KMT2APOLBALDH1A1LMNAHTT | |
| SCHEMBL29414143 | 0.79 | CA1 (0.50) | KMT2APOLBALDH1A1LMNAHTT | |
| SCHEMBL12851817 | 0.78 | SLC22A12 (0.38) | ALDH1A1KDM4ELMNAHTTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |