Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 6/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476299 | 0.93 | MEN1 (0.41) | — | |
| SCHEMBL6851155 | 0.91 | MEN1 (0.38) | SLC2A1 | |
| Tetrahydrothiophene SCHEMBL23420978 | 0.89 | ALDH1A1 (0.39) | IDO1EP300KAT8CDC25BALDH1A1 | |
| SCHEMBL9470141 | 0.86 | GPR3 (0.37) | FABP4 | |
| SCHEMBL6938489 | 0.85 | CYP1A2 (0.43) | FABP4SLC2A1 | |
| SCHEMBL8725902 | 0.84 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL29414143 | 0.84 | CA1 (0.50) | ALDH1A1 | |
| SCHEMBL5599606 | 0.84 | CA1 (0.50) | ALDH1A1 | |
| SCHEMBL29706003 | 0.83 | MEN1 (0.42) | — | |
| SCHEMBL203899 | 0.83 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348071-B2 | Complex fluorene-containing compounds and use | EASTMAN KODAK COMPANY (US) | 2008-03-25 | — | — | US | disclosed |
| US-7285341-B2 | Complex fluorene-containing compounds for use in OLED devices | EASTMAN KODAK COMPANY (US) | 2007-10-23 | — | — | US | disclosed |
| EP-0497342-B1 | Negative photoresist composition | SUMITOMO CHEMICAL CO (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5304456-A | Negative photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0497342-A2 | Negative photoresist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-08-05 | — | — | EP | disclosed |