Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072098 | 1.00 | ESR1 (0.56) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL26088590 | 0.94 | CA2 (0.62) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL17072101 | 0.92 | ESR1 (0.56) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL17072102 | 0.92 | ABL1 (0.46) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL274830 | 0.87 | CA2 (0.71) | ESR1CA2ESR2IGF1RALOX15 | |
| Ammonia Solution, Strong SCHEMBL28306112 | 0.85 | CA2 (0.68) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL3535251 | 0.85 | CA2 (0.54) | CA2ALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL3155617 | 0.83 | ESR1 (0.65) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL2741338 | 0.83 | ESR1 (0.65) | ESR1CA2ESR2IGF1RALOX15 | |
| SCHEMBL378750 | 0.82 | ESR1 (0.48) | ESR1CA2ESR2IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2682448-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-04-20 | — | — | EP | disclosed |
| EP-2682448-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-04-20 | — | — | EP | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133395-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2015-09-15 | — | — | US | disclosed |